TumorMicroenvironment相关论文
Exosome-mediated cell-cell communication within pancreatic cancer tumor microenvironment: a narrativ
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Although abscopal tumor regression remained a rare phenomenon.We generated two distinct tumor models stratified as highl......
嗜酸性粒细胞属于固有免疫细胞，有助于防御寄生虫、细菌和病毒感染，特别是在过敏反应中发挥重要效应。嗜酸性粒细胞浸润多种肿瘤，通过......
A metabolic acidity-activatable calcium phosphate probe with fluorescence signal amplification capab
Dysregulated energy metabolism has recently been recognized as an emerging hallmark of cancer.Tumor cells,which are char......
The Wnt/β-catenin signaling pathway regulates many aspects of tumor biology, and many studies have focused on the role ......
葡萄膜黑色素瘤（UM）是眼内侵袭性强且致命的肿瘤。由于UM及其微环境的复杂性和异质性，导致缺乏早期预防和治疗转移的策略。单细胞测序......
Examining heterogeneity of stromal cells in tumor microenvironment based on pan-cancer single-cell R
Tumor tissues contain both tumor and non-tumor cells, which include infiltrated immune cells and stromal cells, collecti......
Cancer is a serious threat to humans due to its high mortality. The efforts to fully understand cancer and to fight agai......
This decade has seen remarkable advances in the field of high-throughput single cell techniques.Single-cell RNA sequenci......
Development and validation of a tumor microenvironment-related prognostic signature in lung adenocar
Objective Tumor-infiltrating immune cells and stromal cells in the tumor microenvironment (TME) significantly affect the......
唾液酸结合性免疫球蛋白样凝集素（sialic acid-binding Ig-like lectins，SIGLECS）是免疫受体超家族中的主要成员，表达于各类免疫细胞，能......
Basophils, which are considered as redundant relatives of mast cells and the rarest granulocytes in peripheral circulati......
The administration of nanoparticles(NPs)first faces the challenges of evading renal filtration and clearance of reticulo......
Chimeric antigen receptor(CAR)T cell is a novel approach,which utilizes anti-tumor immunity for cancer treatment.As comp......
The prognostic impact of traditional Chinese medicine monomers on tumor-associated macrophages in no
Non-small cell lung cancer (NSCLC) accounts for 80％-85％ of all lung malignancies and good diagnosis and prognosis of NSCLC......
Reversal of Immune-Suppressive Tumour Microenvironment and Induction of Tumouricidal Cascade by Sele
Cancer related death has accounted secondly to the total death.Unfortunately,traditional methods(e.g.radiotherapy or che......
Tumor microenvironment-responsive oligopeptide liposomes for improved druggability of therapeutic an
Liposomes have already had a major impact on improving the druggability,especially the application in antitumor drugs.Li......
Glioma is a malignant primary tumor with the highest intracranial incidence.It is also among the top three cancers,which......
Nanomaterials Prison Cancer by Targeting Tumor Microenvironment as a Specific Inhibitor of Cancer St
The current death rate of cancer is comparable with that in 50 years ago,though numerous progresses havebeen achieved in......
目的 we want to confirm intestinal inflammation can promote the increase of PD-L1expression.Chronic inflammation in the ......
Cynanchum paniculatum and its Major Active Constitutes for Inflammatory Related Diseases and Tumor M
Objective Cynanchum paniculatum Radix,known as Xuchangqing in Chinese,is commonly used in Traditional Chinese Medicine(T......
Objective Scientists have gradually realized that the developing of cancer in human body is actually a process of contin......
目的 The purpose of this study was to investigate the role of LAP+CD4+T cell in pancreatic cancer immunity.方法 LAP and ......
Objective Breast cancer is one of the most common malignancies in women.The abnormal tumor microenvironment is the main ......
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Improved antitumor efficacy of combined vaccine based on the induced HUVECs and DC-CT26 against colo
Objective Angiogenesis is essential for the development,growth,and metastasis of solid tumors....
A 19F-MR imaging Probe for Enhance Radiotherapy by Improve Tumor Oxygenation and Lung Cancer Therape
Objective Tumor microenvironments(TME)present an important characteristic for solid tumors due to their complex structur......
Objective Increasing evidence show that the malignant behavior of cancer is not exclusively attributable to cancer cells......
Reprogramming bone microenvironment by DNA-loaded cationic lipid nanoparticles to inhibit T cell acu
Objective T cell acute lymphoblastic leukemias(T-ALLs)are aggressive hematologic disorders resulting from the malignant ......
Programmed Death Ligand 1 expression in human intrahepatic cholangiocarcinoma and its association wi
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Objective Cancer immunotherapy has ushered in a new era of anti-tumor therapy and is developing at a dramatic rate....
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Background& Objective: Tumor-associated macrophages (TAM) are induced by many cytokines, such as IL-4, IL-10,IL-13, and ......
Objective: The Cancer Genome Atlas has proposed four new molecular characterizations gastric adenocarcinoma,including Ep......
TREM-1low is a novel marker for Tumor-associated macrophages in tumor microenvironment and associate
Objection: TREM-1 is a crucial molecule for triggering and magnifying inflammatory responses and plays an important role......
Background: TSP50 (Testes-specific protease 50) was abnormally overexpressed in many kinds of cancer tissues and it has ......
Maspin Inhibits Macrophage Phagocytosis and Enhances Pro-inflammatory Cytokines Production via the A
Background: Maspin (mammary serine protease inhibitor) is a non-inhibitory member of the serine protease inhibitor super......
Function and mechanism of IL-36β on promoting antitumor immune response through activating CD8+T cel
Background: Cytokines play a pivotal role in breaking immune tolerance of tumor antigens and increase response rates to ......
Integrin β3-associated microenvironment promotes invasion and angiogenesis in EGFRvⅢ-expressing glio
Backgroud: Glioblastoma (GBM) is one of the most lethal brain tumors with a short survival time.Expression of a variant ......
Selective Autophagy Sustains the Survival and Pro-tumorigenic Effects of Tumor-Associated Neutrophil
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Chinese medicine Bu-Fei Decoction (BFD) attenuates epithelial-mesenchymal transition of non-small ce
Objective: Traditional Chinese medicine Bu-Fei Decoction (BFD) containing six species of herbs has been used to treat lu......
A non-negligibly representative non-tumor cells-tumor associated fibroblast cells(CAFs)has a very important effect on tu......
Mechanisms of tumor cells selectively packaging and releasing Exosomes and its regulating Role in Tu
Nonresolving inflammation (NRI) plays an important role in the initiation, development and neoplastic transformation of ......
Pancreatic cancer is a devastating disease with proclivity for early metastasis,which accounts for its poor prognosis....
Over the last decades,the development of novel cancer therapeutics is often plagued by discrepancies between drug effica......
Studies from tumor cells suggest that tumor-suppressor AIP1 inhibits epithelial-mesenchymal transition (EMT).However, th......
肺癌是恶性肿瘤导致死亡的首要原因。阐明肺癌的发病机制，研制有效的防治手段具有重要意义。已经证明肺癌的发生发展与CD4+T细胞的......
A Novel Recombinant hyaluronidase PH20-Fc Targets Tumor Architecture to Favor Drug Penetration for S
The tumour microenvironment, which is conventionally characterized by increased interstitial fluid pressure (IFP), lowed......
